bio-comparative-genomics-synteny-analysis
GPTomics · Other
使用 MCScanX (Wang 2012)、JCVI/MCScan (Tang 2008 Python)、GENESPACE (Lovell 2022) 进行直系同源锚定的河岸可视化、SyRI 进行结构变异、AnchorWave 进行序列级共线性、i-ADHoRe 3.0 用于高度分化物种、SynNet 用于共线性网络、ntSynt 用于多基因组宏共线性，检测基因组间的共线性块和结构重排。用于识别跨物种的共线基因块、区分宏共线与微共线、检测倒位/易位/重复、在 WGD 谱系中锚定直系同源、生成出版级河岸图、通过 Ks 计算共线性块年龄（交叉参考全基因组复制），或在多倍体中进行共线性感知的直系同源推断。
Detect syntenic blocks and structural rearrangements between genomes using MCScanX (Wang 2012), JCVI/MCScan (Tang 2008 Python), GENESPACE (Lovell 2022) for orthology-anchored riparian visualization, SyRI for structural variation, AnchorWave for sequence-level synteny, i-ADHoRe 3.0 for highly diverged species, SynNet for synteny networks, and ntSynt for multi-genome macrosynteny. Use when identifying collinear gene blocks across species, distinguishing macrosynteny from microsynteny, detecting inversions/translocations/duplications, anchoring orthology in WGD lineages, producing publication riparian plots, computing synteny block age via Ks (cross-references whole-genome-duplication), or running synteny-aware ortholog inference in polyploids.
npx skills add https://github.com/GPTomics/bioSkills --skill synteny-analysis
星标 895 · 安装量 0